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Stephen J. Stray, Ph.D. |
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Assistant Professor
B.Sc. (Honors), Melbourne, Australia, 1988
Ph.D., University of Alabama, Birmingham, 2000
Primary Research Interests:
a) Hepatitis B
b) Influenza Virus
c) Virus Assembly
The assembly of virus particles is strictly regulated in infected cells. The steps of virus replication and assembly have to occur both in the right order (temporal regulation) and in the right location in the different in different compartments of the cell (topological regulation). I am interested in influenza and Hepatitis B viruses because they are major human pathogens. These viruses are unusual because replication of each virus involves both nuclear and cytoplasmic events. Viral proteins must interact with the host cell machinery and with other viral proteins in order to be targetted to the right place in the cell at the appropriate time in the viral life cycle. I study these interactions both in tissue culture and using purified proteins in vitro. These interactions between may provide an important target for antiviral drugs.
Publications:
PubMed Search made 3/21/07
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